For site specific delivery, lipid nanoparticles (LNPs) modified with ligands are widely used. SUNBRIGHT GS-020TS is a functionalized PEG lipid designed for efficient ligand conjugation in LNP drug delivery systems. It features two C18:0 fatty acids (18 carbon atoms, no double bonds, stearic acid) connected at the 1- and 2-positions of a glycerol backbone, with a 2,000 Da polyethylene glycol (PEG) chain linked at the 3-position and terminated with an NHS carbonate group. The NHS carbonate group allows conjugation with amine-containing molecules to form a stable carbamate bond. GS-020TS does not have a charge that could adversely affect the stability of LNPs and is useful for developing active targeting delivery systems.
Chemical Name: 1,2-Distearoyl-rac-glycero-3-(succinimidyloxycarbonyl)polyoxyethylene
CAS#:
PEG chain Molecular weight: 2000
RCOO= C18:0
Package size: 100mg or 1g
