COATSOME ME-8080 (DSPE), or 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine, is a ≥99% pure synthetic phospholipid. Featuring C18:0 fatty acids (18 carbon atoms, no double bonds, stearic acid) at both the sn-1 and sn-2 positions, DSPE provides a small phosphoethanolamine headgroup, promoting membrane curvature and facilitating membrane fusion in lipid-based formulations.
DSPE is suitable for liposomal and lipid nanoparticle (LNP) formulations, and supports the development of advanced drug delivery systems requiring enhanced membrane fusion or endosomal escape. Manufactured using highly purified fatty acids, ME-8080 offers consistent quality for pharmaceutical research and clinical applications.
Acronym: DSPE
Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine
CAS#: 1069-79-0
PE purity: 99% up
Molecular weight: 748.1
Alkyl composition: R1COO= C18:0, R2COO= C18:0
