For site specific delivery, lipid nanoparticles (LNPs) modified with ligands are widely used. SUNBRIGHT GS-050TS is a functionalized PEG lipid designed for efficient ligand conjugation in LNP drug delivery systems. It features a NHS carbonate group linked to a PEG diacylglycarol (DSG-PEG5000), allowing conjugation with amine-containing molecules to form stable carbamate bond. GS-050TS does not have a charge that could adversely affect the stability of LNPs and is useful for developing active targeting delivery systems.
DSG-PEG-COO-NHS, PEG MW 5,000
Chemical Name: 1,2-Distearoyl-rac-glycero-3-(succinimidyloxycarbonyl) polyoxyethylene
CAS#: 3079792-07-4
RCOO= C18:0
Package size: 100mg or 1g
