Drug Delivery

SUNBRIGHT® GS-050DB2*

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For site specific delivery, lipid nanoparticles (LNPs) modified with ligands are widely used. SUNBRIGHT GS-050DB2 is a functionalized PEG lipid designed for efficient ligand conjugation in LNP drug delivery systems. It features a maleimide group linked to a PEG diacylglycarol (DSG-PEG5000), which allows selective conjugation with thiol-containing molecules such as peptides or antibodies, and enables precise cellular targeting and enhanced formulation versatility of LNPs. GS-050DB2  does not have a charge that could adversely affect the stability of LNPs and is useful for developing active targeting delivery systems.

DSG-PEG-DBCO, PEG MW 5,000
Chemical Name: 1,2-Distearoyl-rac-glycero-3-{(3’-azadibenzocyclooctyne-3’-oxopropyl)aminocarbonyl} polyoxyethylene
RCOO= C18:0

*: make-to-order

Package size: 100mg

Alkyl Composition RCOO= C18:0
Applications Gene and Nucleic Acid Delivery
Chemical Name 1,2-Distearoyl-rac-glycero-3-{(3’-azadibenzocyclooctyne-3’-oxopropyl)aminocarbonyl} polyoxyethylene
Functional Groups DBCO
MW 5,000
Package Size 100mg
Product categories Activated PEG Lipids
Target Groups Azide
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