For site specific delivery, lipid nanoparticles (LNPs) modified with ligands are widely used. SUNBRIGHT GS-034MA is a functionalized PEG lipid designed for efficient ligand conjugation in LNP drug delivery systems. It features a maleimide group linked to a PEG diacylglycarol (DSG-PEG3400), which allows selective conjugation with thiol-containing molecules such as peptides or antibodies, and enables precise cellular targeting and enhanced formulation versatility of LNPs. GS-034MA does not have a charge that could adversely affect the stability of LNPs and is useful for developing active targeting delivery systems.
DSG-PEG-Maleimide, PEG MW 3,400
Chemical Name: 1,2-Distearoyl-rac-glycero-3-(2'-maleimidoethyl) polyoxyethylene
CAS#: 2765451-87-2
RCOO= C18:0
Package size: 100mg or 1g