SUNBRIGHT® GL2-400MA3

  • SUNBRIGHT® GL2-400MA3
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SUNBRIGHT GL2-400MA3 is a 2-arm branched maleimide-PEG with a total molecular weight of 40 kDa (20 kDa per PEG arm). The maleimide group site-specifically reacts with thiol groups on bioactive molecules (e.g., proteins, peptides, and other biologics), resulting in highly efficient and quantitative PEGylation. Both its maleimide group and the resulting maleimide–thiol conjugates exhibit enhanced resistance to hydrolysis compared with the MA type because of their different chemical structures. We originally developed and introduced this type of 2-arm branched activated PEG, which has already been successfully utilized in several marketed PEGylated drugs, demonstrating its practical utility and reliability in therapeutic applications.


Applications
Protein and Peptide Conjugate
CAS Registry Number
1422174-72-8
Chemical Formula
2arm branched PEG, -(CH2)3NHCO(CH2)5-MAL
Chemical Name
2,3-Bis(methylpolyoxyethylene-oxy)-1-{[3-(6-maleimido-1-oxohexyl)amino]propyloxy} hexane
Functional Groups
Maleimide
MW
40,000
Package Size
100mg
PEG Type
Branched PEGs
Target Groups
Thiol
Title
$110.00
$110.00
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