New Linkers for Antibody Drug Conjugates (ADCs)

 

NOF CORPORATION would like to announce the launch of our newest product, PUREBRIGHT® Series of single molecular weight PEG reagents.  PUREBRIGHT® Series have demonstrated usefulness in many applications, particularly as linkers for Antibody Drug Conjugates (ADCs) to increase conjugate hydrophilicity and drug payload.

 

PUREBRIGHT® Series are manufactured by our proprietary synthesis process to have very low isomer impurity (different numbers of ethylene glycol units) and high activation purity.

 

Key advantages of NOF’s PUREBRIGHT® Series are:

  • Precise control of the number of ethylene glycol units (i.e. PEG molecular weight) with high purity (available with 4, 8, 12 and 24 ethylene glycol units);
  • Available in a combination of functional groups with linear, branched and pendant type structures;
  • Scalable under cGMP condition (up to kilogram scale); and
  • Reliable analytical method to determine the purity.

 

For more information, contact our regional offices.

[Americas]
NOF AMERICA CORPORATION
E-mail: info@nofamerica.com
Tel: NY Office: +1-914-681-9790 (Ext. 120)
CA Office: +1-949-253-5764

[Europe]
NOF EUROPE GmbH
E-mail: info@nofeurope.com
Tel: +49-069-7706-100-0

[Asia Pacific, Japan]
NOF CORPORATION
DDS Development Division
E-mail: ddsinfo@nof.co.jp

[China]
NOF (Shanghai) Co. Ltd.
E-mail: info@nof.cn
Tel: +86-21-6210-1100