Lipidure®-CM (MPC polymer)

NOF is pleased to announce that a Device Master File has been submitted to the FDA for Lipidure®-CM5206.  The Lipidure®-CM5206 Master File contains important confidential information regarding the composition and manufacturing information needed as part of a medical device submission to the FDA.

 

Chemical structure


Coating Method

 

Available substrate

Lipidure®-CM5206 can be coated on the following materials

 

Feature

 

 

・Suppression of protein adsorption


<<Method>>

1. Prepare well plate coated with Lipidure®-CM5206
2. Add HRP-IgG conjugate solution into each well
3. Incubate for 1 hr at 25 ºC
4. Rinse three times with 0.05 % Tween®20 (*) /Dulbecco’s PBS
5. Add of 3,3’,5,5’-tetramethylbenzidine solution into each well
6. Measure absorbance at 450 nm

*Tween® is a registered trademark of Croda International PLC.

 

 

 

・Suppression of cell adsorption


<<Method>>

1. Prepare well plate coated with Lipidure®-CM5206
2. Seed macrophage in well plate at 3.3x105 cells/well
3. Incubate for 1 hr at 37 ºC in 5% CO2 atmosphere
4. Rinse off with Dulbeco’s PBS
5. Fix with glutaraldehyde and Observation by SEM

 

 

 

・Hemo-compatibility


<<Method>>

1. Prepare artificial vascular coated with Lipidure®-CM5206
2. Rabbit blood was flowed in Lipidure®-CM5206 treated artificial vascular
3. Rinse artificial vascular with buffer solution
4. Take photo of inside of artificial vascular

 

 

$300.00
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Minimum quantity for "Lipidure®-CM5206 (1g)" is 1.

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$1,500.00
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